With government grants and personal funding, using our patented and patent-pending technologies and treatment protocol, we have successfully demonstrated our HET technology, have used AdvaNan successfully in animals, and have successfully treated cancer in mice and dogs.
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*Cancer cell destruction by Holothermia
The Holothermia protocol - Powered by HET technology
HET (Holographic Energy Teleportation) is Holobeam's patented new technology which uses holography, in a new way, to teleport energy from its source to distant precisely-selected microscopic locations, without appearing to pass through the intervening space (which, after all, is the purpose of teleportation). Thus, HET allows us to send energy to tissue regions, or even individual cells, within a patient, one at a time, to gather data about the chemistry, biology, physics, metabolic status, malignancy, and disease condition at each point. The obtained data enables us to produce real-time color holographic 3-D imagery, still or moving, for early diagnosis.
This capability also allows us to generate heat within the patient, just at precisely-selected locations, to enhance therapies like radiation treatment, chemotherapy, and hyperthermia, providing treatment (even during diagnosis) with greatly improved efficacy, along with utmost safety, eliminating side effects. Our breakthrough will allow for successful treatment of tumors that are currently inoperable and generally untreatable, such as glioblastoma multiforme, without side effects.
Using HET for diagnosis and treatment is the Holothermia protocol. Holothermia is designed to find and efficiently help destroy cancer cells.
When a cancerous tumor is detected in a patient with conventional imaging, such as an x-ray, CT scan, MRI scan, or PET scan, it is at least 1/10th of a millimeter in size, and usually much larger. At that point, millions of cancer cells have already assembled, and some of them have begun traveling within the body (called metastasis) away from their original formation location. Nearly 95% of all cancer deaths are due to metastasis. Once cancer cells are found, conventional treatments can be directed towards them, but at that stage, the results are not always favorable.
This is why Holobeam developed AdvaNan nanoparticles. With HET and AdvaNan together, individual malignant cells can be detected and located, providing much earlier detection, when highly successful treatment is more likely.
Cancer cells and cancer stem cells have structures on their exteriors, called "antigens," that are unique for each type of cancer. The immune system is constantly experimenting with proteins, throwing them together in different combinations, and folding them into different shapes. These protein conglomerations are called antibodies. It has recently been postulated that the human immune system is capable of producing a quintillion different antibodies. Consequently, the immune system is capable of producing antibodies that will attach to any type of cell antigen, like a key fits into a lock, connecting them together. However, only rarely are such antibodies also "neutralizing," meaning that the antibody will somehow disable or destroy the cancer cell that it is connected to. Nevertheless, over 2000 different antibodies have already been extracted, identified, cloned (making them "monoclonal antibodies"), and FDA approved for use with patients to treat different diseases, and the number continues to grow.
Holobeam uses such monoclonal antibodies to direct our unique nanoparticles to specific types of cancer cells. Our nanoparticles are bound to monoclonal or polyclonal (meaning many) antibodies to direct them to specific targeted cells. However, unlike with other disease treatments, the antibodies we use do not have to be neutralizing, giving us a wider range of antibodies to choose from. Their sole purpose is to attach our nanoparticles to individual types of cancer cells or groups of cells. That allows AdvaNan to attach, in large numbers, mostly just to targeted cancer cells.
Once the nanoparticles are connected to the target cancer cells, we use HET to send energy to them. Our nanoparticles are designed to absorb a maximum amount of the energy sent to them, and also to convert that energy as efficiently as possible to heat. This method improves the efficacy and safety of cancer treatments by generating significant heating only in the nanoparticles attached to cancerous cells, leaving healthy cells unharmed, avoiding side effects. This is the Holothermia protocol with AdvaNan nanoparticles.
Holobeam is developing two types of scanners that use HET for diagnosis and treatment.
The HET MRI scanner looks and works a lot like a modern-day MRI. However, as described elsewhere on this site, it has many advantages over a conventional MRI system, allowing for earlier detection as well as treatment, which current MRI systems are not capable of.
The Portable HET Scanner is also capable of earlier detection as well as treatment. However, as explained elsewhere on this site, it has several advantages over the HET MRI system.
Both systems can be used to detect and treat tumors with or without AdvaNan nanoparticles.